NFAT2 antibody

GeneTex

NFAT2 antibody

9

The amino acid sequence used is 90% homologous in mouse and rat and 100% identical in human NFATc1 A, B, C and E isoforms. The reported amino acid size of NFATc1 isoforms are as follows: A -716 aa, B-825 aa, C-930 aa, and E-812 aa.

WB: 1 - 3 microg/ml. ICC/IF: 1:20. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NFATC1

nuclear factor of activated T cells 1

NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NF-ATc1.2; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Rabbit

IgG

Nuclear factor of activated T-cells, cytoplasmic 1

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203