Oct4 antibody
GTX101497
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPOU5F1
Overview
- SupplierGeneTex
- Product NameOct4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:100000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5460
- Target namePOU5F1
- Target descriptionPOU class 5 homeobox 1
- Target synonymsOCT3; Oct-3; OCT4; Oct-4; octamer-binding protein 3; octamer-binding protein 4; octamer-binding transcription factor 3; OTF3; OTF-3; OTF4; POU domain transcription factor OCT4; POU domain, class 5, transcription factor 1; POU-type homeodomain-containing DNA-binding protein
- HostRabbit
- IsotypeIgG
- Protein IDQ01860
- Protein NamePOU domain, class 5, transcription factor 1
- Scientific DescriptionThis gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewings sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma.Read more
- Cbx7 promotes the generation of induced pluripotent stem cells.Read more
- Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic Markers.Read more
- Alanine-Glyoxylate Aminotransferase Sustains Cancer Stemness Properties through the Upregulation of SOX2 and OCT4 in Hepatocellular Carcinoma Cells. Ye P et al., 2022 May 5, BiomoleculesRead more
- Generation of a DKK2 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system. Zhang W et al., 2021 Nov 24, Stem Cell ResRead more
- Nuclear receptor 4A1 (NR4A1) antagonists target paraspeckle component 1 (PSPC1) in cancer cells.Read more
- High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts. Salti A et al., 2021 Aug 10, CellsRead more
- Mesenchymal stem cell-derived exosomal miR-146a reverses diabetic beta-cell dedifferentiation. He Q et al., 2021 Aug 11, Stem Cell Res TherRead more
- Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages. Wang YY et al., 2020 Nov 26, Cancers (Basel)Read more
- Prognostic value of OCT4 in colorectal cancer: analysis using immunohistochemistry and bioinformatics validation. Fang W et al., 2020 Oct, Biomark MedRead more