WB analysis of EGF-treated HEK293T (A), MCF7 (B), NIH3T3 (C), EGF-treated Raw264.7 (D), EGF-treated H9C2 (E) whole cell lysates using GTX55090 p27 Kip1 (phospho Thr198) antibody.
WB analysis of EGF-treated HEK293T (A), MCF7 (B), NIH3T3 (C), EGF-treated Raw264.7 (D), EGF-treated H9C2 (E) whole cell lysates using GTX55090 p27 Kip1 (phospho Thr198) antibody.
p27 Kip1 (phospho Thr198) antibody
GTX55090
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDKN1B
Overview
- SupplierGeneTex
- Product Namep27 Kip1 (phospho Thr198) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1027
- Target nameCDKN1B
- Target descriptioncyclin dependent kinase inhibitor 1B
- Target synonymsCDKN4; cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); KIP1; MEN1B; MEN4; P27KIP1
- HostRabbit
- IsotypeIgG
- Protein IDP46527
- Protein NameCyclin-dependent kinase inhibitor 1B
- Scientific DescriptionThis gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Carnosic acid impedes cell growth and enhances anticancer effects of carmustine and lomustine in melanoma. Lin KI et al., 2018 Aug 31, Biosci RepRead more