PCNA antibody
GTX100539
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Hamster, Human, Mouse, Rat
TargetPCNA
Overview
- SupplierGeneTex
- Product NamePCNA antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.11 mg/ml
- ConjugateUnconjugated
- Gene ID5111
- Target namePCNA
- Target descriptionproliferating cell nuclear antigen
- Target synonymsATLD2, proliferating cell nuclear antigen, DNA polymerase delta auxiliary protein, cyclin
- HostRabbit
- IsotypeIgG
- Protein IDP12004
- Protein NameProliferating cell nuclear antigen
- Scientific DescriptionThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq]
- ReactivityDrosophila, Hamster, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Su HY, Lai CS, Lee KH, et al. Prenatal exposure to low-dose di-(2-ethylhexyl) phthalate (DEHP) induces potentially hepatic lipid accumulation and fibrotic changes in rat offspring. Ecotoxicol Environ Saf. 2024,269:115776. doi: 10.1016/j.ecoenv.2023.115776Read this paper
- Brzozowa-Zasada M, Ianaro A, Piecuch A, et al. Immunohistochemical Expression of Glutathione Peroxidase-2 (Gpx-2) and Its Clinical Relevance in Colon Adenocarcinoma Patients. Int J Mol Sci. 2023,24(19). doi: 10.3390/ijms241914650Read this paper
- Arellano Buendia AS, Juárez Rojas JG, García-Arroyo F, et al. Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome. PeerJ. 2023,11:e16132. doi: 10.7717/peerj.16132Read this paper
- Brzozowa-Zasada M, Piecuch A, Michalski M, et al. Immunohistochemical Expression of Upregulated Gene 4 Protein Expression (URG4/URGCP) and Its Association with 5-Year Survival in Patients with Colon Adenocarcinoma. J Clin Med. 2023,12(17). doi: 10.3390/jcm12175477Read this paper
- Alibardi L. Immunolocalization of Some Epidermal Proteins and Glycoproteins in the Growing Skin of the Australian Lungfish (Neoceratodus forsteri). J Dev Biol. 2023,11(3). doi: 10.3390/jdb11030035Read this paper
- Brzozowa-Zasada M, Piecuch A, Bajdak-Rusinek K, et al. Immunohistochemical Expression of Glutathione Peroxidase 1 (Gpx-1) as an Independent Prognostic Factor in Colon Adenocarcinoma Patients. Pharmaceuticals (Basel). 2023,16(5). doi: 10.3390/ph16050740Read this paper
- Brzozowa-Zasada M, Piecuch A, Michalski M, et al. The Clinical Application of Immunohistochemical Expression of Notch4 Protein in Patients with Colon Adenocarcinoma. Int J Mol Sci. 2023,24(8). doi: 10.3390/ijms24087502Read this paper
- Nee K, Ma D, Nguyen QH, et al. Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis. Nat Genet. 2023,55(4):595-606. doi: 10.1038/s41588-023-01298-xRead this paper
- Zhang W, Fan Z, Wang F, et al. Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3. Oxid Med Cell Longev. 2023,2023:9966355. doi: 10.1155/2023/9966355Read this paper
- Fang ZM, Zhang SM, Luo H, et al. Methyltransferase-like 3 suppresses phenotypic switching of vascular smooth muscle cells by activating autophagosome formation. Cell Prolif. 2023,56(4):e13386. doi: 10.1111/cpr.13386Read this paper
Datasheet
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