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ProductsBack/PLK1 antibody [1D4]
IHC-P analysis of human breast adenocarcinoma tissue using GTX83865 PLK1 antibody [1D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human breast adenocarcinoma tissue using GTX83865 PLK1 antibody [1D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human breast adenocarcinoma tissue using GTX83865 PLK1 antibody [1D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.

PLK1 antibody [1D4]

GTX83865
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetPLK1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PLK1 antibody [1D4]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:2000. IHC-P: 1:150. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D4
  • Concentration
    2.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5347
  • Target name
    PLK1
  • Target description
    polo like kinase 1
  • Target synonyms
    cell cycle regulated protein kinase; PLK; PLK-1; polo (Drosophia)-like kinase; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP53350
  • Protein Name
    Serine/threonine-protein kinase PLK1
  • Scientific Description
    Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203