PPP1R12A Polyclonal Antibody

Reddot Biotech

PPP1R12A Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

PPP1R12A

protein phosphatase 1 regulatory subunit 12A

GUBS; M130; MBS; myosin binding subunit; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; MYPT1; protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase myosin-binding subunit

Rabbit

IgG

Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.

Human, Mouse, Rat

-20°C

12352203