FACS analysis of HepG2 cells using GTX57230 PXR antibody. Green : Primary antibody Orange : Isotype control antibody Fixation : 4% PFA for 10min at room temperature Permeabilization : 90% ice-cold methanol for 20 min at -20oC Dilution : 1:500
FACS analysis of HepG2 cells using GTX57230 PXR antibody. Green : Primary antibody Orange : Isotype control antibody Fixation : 4% PFA for 10min at room temperature Permeabilization : 90% ice-cold methanol for 20 min at -20oC Dilution : 1:500
PXR antibody
GTX57230
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetNR1I2
Overview
- SupplierGeneTex
- Product NamePXR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:300-1:1000. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID8856
- Target nameNR1I2
- Target descriptionnuclear receptor subfamily 1 group I member 2
- Target synonymsBXR; nuclear receptor subfamily 1 group I member 2; ONR1; orphan nuclear receptor PAR1; orphan nuclear receptor PXR; PAR; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; pregnane X receptor; PRR; PXR; SAR; steroid and xenobiotic receptor; SXR
- HostRabbit
- IsotypeIgG
- Protein IDO75469
- Protein NameNuclear receptor subfamily 1 group I member 2
- Scientific DescriptionThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Porcine, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203