More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Sheep anti Human chx 10 (Visual system homeobox 2) (NT)

Sheep anti Human chx 10 (Visual system homeobox 2) (NT)

Research Use Only
X1180P
Nordic-MUbio
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityChicken, Human, Mouse, Rat
TargetVSX2
Price on request
250 ug
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Sheep anti Human chx 10 (Visual system homeobox 2) (NT)
  • Delivery Days Customer
    7
  • Antibody Specificity
    Human Chx10 protein
  • Application Supplier Note
    Detects Chx10 by Western blot at 0.5 to 1 microg/ml. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Applications Supplier
    Western Blotting;Immunohistochemistry (frozen);Immunohistochemistry (frozen)
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID338917
  • Target name
    VSX2
  • Target description
    visual system homeobox 2
  • Target synonyms
    ceh-10 homeo domain containing homolog; ceh-10 homeodomain-containing homolog; CHX10; homeobox protein CHX10; HOX10; MCOP2; MCOPCB3; RET1; visual system homeobox 2
  • Host
    Sheep
  • Isotype
    IgG
  • Protein IDP58304
  • Protein Name
    Visual system homeobox 2
  • Scientific Description
    Ceh-10 homeodomain-containing homolog
  • Shelf life instruction
    See expiration date on vial
  • Source
    Antibody raised in sheep against a recombinant protein corresponding to amino acids 1 to 131 derived from the N-terminal region of the human Chx10 protein conjugated to KLH.
  • Reactivity
    Chicken, Human, Mouse, Rat
  • Reactivity Supplier
    Human;Mouse;Rat;Chicken
  • UNSPSC
    12352203

References

  • 1. Liu, I.S., et al. Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 1994, 13, 377-393 2. Chen, C.M. & Cepko, C.L. Expression of Chx10 and Chx10-1 in the developing chicken retina. Mech. Dev. 2000, 90, 293-297 3. Ferda Percin, E., et al. Human microphthalmia associated with mutations in the retinal homeobox gene CHX10. Nat. Genet. 2000, 25, 397-401 4. Nittner, D., et al. Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation. Nature Cell Biology (2012), 14, 958-965 5. Kay, J.N., et al. Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate. Nature Neuroscience (2011), 14, 965-972 6. Eiraku, M., et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature (2011), 472, 51-56 7. Pierfelice, T.J., et al. Notch3 Activation Promotes Invasive Glioma Formation in a Tissue Site-Specific Manner. Cancer Res., 71, 1115-1125 (2011). 7. Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis https://doi.org/10.1186/s13024-018-0287-z 8. Anastasia Marie Litke; Sarah Samuelson; Kerry R. Delaney; Yves Sauvé; Robert L. Chow Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease Investigative Ophthalmology & Visual Science December 2018, Vol.59, 5824-5835. doi:10.1167/iovs.18-2549