SIRT1 antibody

GeneTex

SIRT1 antibody

9

WB: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

SIRT1

sirtuin 1

SIR2, SIR2L1, SIR2alpha, NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacylase sirtuin-1, SIR2-like protein 1, regulatory protein SIR2 homolog 1, sirtuin type 1

Rabbit

IgG

NAD-dependent protein deacetylase sirtuin-1

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

-20°C or -80°C,2°C to 8°C

12352203