IP analysis of Jurkat cell lysate using GTX17532 SIRT1 antibody. Antibody amount : 3microg / 200microg lysate Dilution : 1:1000
IP analysis of Jurkat cell lysate using GTX17532 SIRT1 antibody. Antibody amount : 3microg / 200microg lysate Dilution : 1:1000
SIRT1 antibody
GTX17532
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSIRT1
Overview
- SupplierGeneTex
- Product NameSIRT1 antibody - KO/KD Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID23411
- Target nameSIRT1
- Target descriptionsirtuin 1
- Target synonymsNAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacylase sirtuin-1; regulatory protein SIR2 homolog 1; SIR2; SIR2alpha; SIR2L1; SIR2-like protein 1; sirtuin type 1
- HostRabbit
- IsotypeIgG
- Protein IDQ96EB6
- Protein NameNAD-dependent protein deacetylase sirtuin-1
- Scientific DescriptionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice. Braud L et al., 2021 Jan, Redox BiolRead more
- Kidney dysfunction induced by a sucrose-rich diet in rat involves mitochondria ROS generation, cardiolipin changes, and the decline of autophagy protein markers. Ruiz-Ramirez A et al., 2020 Jan 1, Am J Physiol Renal PhysiolRead more
- Liraglutide protects against glucolipotoxicity-induced RIN-m5F beta-cell apoptosis through restoration of PDX1 expression. Kornelius E et al., 2019 Jan, J Cell Mol MedRead more