
Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with SOD2 antibody (GTX116093) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
SOD2 antibody
GTX116093
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Human, Mouse, Reptile, Rat
TargetSOD2
Overview
- SupplierGeneTex
- Product NameSOD2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.24 mg/ml
- ConjugateUnconjugated
- Gene ID6648
- Target nameSOD2
- Target descriptionsuperoxide dismutase 2
- Target synonymsGC1, GClnc1, IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD, lncRNA-GC1, superoxide dismutase [Mn], mitochondrial, Mn superoxide dismutase, epididymis secretory sperm binding protein, gastric cancer-associated lncRNA 1, indophenoloxidase B, manganese-containing superoxide dismutase, mangano-superoxide dismutase, superoxide dismutase 2, mitochondrial
- HostRabbit
- IsotypeIgG
- Protein IDP04179
- Protein NameSuperoxide dismutase [Mn], mitochondrial
- Scientific DescriptionThis gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
- ReactivityAvian, Human, Mouse, Reptile, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Kogami M, Abe S, Nakamura H, et al. Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro. Oncol Lett. 2023,26(1):313. doi: 10.3892/ol.2023.13899Read this paper
- Mesquita PHC, Osburn SC, Godwin JS, et al. Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats. Physiol Rep. 2022,10(24):e15542. doi: 10.14814/phy2.15542Read this paper
- Ma PW, Wang WL, Chen JW, et al. Treatment with the Ferroptosis Inhibitor Ferrostatin-1 Attenuates Noise-Induced Hearing Loss by Suppressing Ferroptosis and Apoptosis. Oxid Med Cell Longev. 2022,2022:3373828. doi: 10.1155/2022/3373828Read this paper
- Kornelius E, Tsou SH, Chang CC, et al. Liraglutide Attenuates Glucolipotoxicity-Induced RSC96 Schwann Cells' Inflammation and Dysfunction. Biomolecules. 2022,12(10). doi: 10.3390/biom12101338Read this paper
- Wu YL, Chang JC, Chao YC, et al. In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3. Antioxidants (Basel). 2022,11(7). doi: 10.3390/antiox11071389Read this paper
- Sulistyowati E, Hsu JH, Lee SJ, et al. Potential Actions of Baicalein for Preventing Vascular Calcification of Smooth Muscle Cells In Vitro and In Vivo. Int J Mol Sci. 2022,23(10). doi: 10.3390/ijms23105673Read this paper
- Mallard J, Hucteau E, Charles AL, et al. Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. J Cachexia Sarcopenia Muscle. 2022,13(3):1896-1907. doi: 10.1002/jcsm.12991Read this paper
- Chen JW, Ma PW, Yuan H, et al. mito-TEMPO Attenuates Oxidative Stress and Mitochondrial Dysfunction in Noise-Induced Hearing Loss via Maintaining TFAM-mtDNA Interaction and Mitochondrial Biogenesis. Front Cell Neurosci. 2022,16:803718. doi: 10.3389/fncel.2022.803718Read this paper
- Li J, Wang J, Li Y, et al. Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway. Ecotoxicol Environ Saf. 2021,228:112918. doi: 10.1016/j.ecoenv.2021.112918Read this paper










![WB analysis of various samples using GTX09013 SOD2 antibody [GT1165]. Dilution : 1:1000 Loading : 25 μg](https://www.genetex.com/upload/website/prouct_img/normal/GTX09013/GTX09013_20200508_WB_w_23053123_761.webp)

![SOD2 antibody [GT582] detects SOD2 protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg A431 whole cell lysate/extract C. 30 μg HeLa whole cell lysate/extract | D. 30 μg HepG2 whole cell lysate/extract 12 % SDS-PAGE SOD2 antibody [GT582] (GTX630558) dilution: 1:5000](https://www.genetex.com/upload/website/prouct_img/normal/GTX630558/GTX630558_41589_WB_w_23061202_990.webp)
![SOD2 antibody [GT1433] detects SOD2 protein by western blot analysis. A. 50 μg rat brain lysate/extract 12 % SDS-PAGE SOD2 antibody [GT1433] (GTX630559) dilution: 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX630559/GTX630559_41589_WB_R_brain_w_23061202_222.webp)
![SOD2 antibody [GT17112] detects SOD2 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. SOD2 stained by SOD2 antibody [GT17112] (GTX630560) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX630560/GTX630560_41589_20180629_IHC-P_w_23061202_309.webp)
![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with SOD2 (Acetyl Lys68) antibody [HL1460] (GTX636934) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX636934/GTX636934_44788_20220902_WB_B_22092119_512.webp)
![SOD2 antibody [HL1483] detects SOD2 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. SOD2 stained by SOD2 antibody [HL1483] (GTX636957) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX636957/GTX636957_T-44669_20220617_IHC-P_22062121_897.webp)