TNF Receptor I antibody
GTX102710
Overview
- SupplierGeneTex
- Product NameTNF Receptor I antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7132
- Target nameTNFRSF1A
- Target descriptionTNF receptor superfamily member 1A
- Target synonymsCD120a; FPF; p55; p55-R; p60; TBP1; TNFAR; TNF-R; TNFR1; TNF-R1; TNFR55; TNF-R55; TNFR60; TNF-RI; TNF-R-I; TNFR-I; tumor necrosis factor binding protein 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor-alpha receptor
- HostRabbit
- IsotypeIgG
- Protein IDP19438
- Protein NameTumor necrosis factor receptor superfamily member 1A
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203