TNFRSF1A / TNFR1 Antibody (clone R111, Preservative Free)

LifeSpan BioSciences

TNFRSF1A / TNFR1 Antibody (clone R111, Preservative Free)

14

Block: In a functional ELISA which immobilized recombinant Human TNFR1 at 0.2 ug/ml (100 microL/well) in the plate, the Rabbit anti-Human Monoclonal Antibody can block the binding of 0.5 ug/ml of biotinylated Human TNFa to human TNFR1, the EC50 is 4. 66 ug/ml. Neutralization: The neutralization activity of TNFR1/TNFRSF1A Neutralizing Antibody is Measured by its ability to neutralize TNFR1/TNFRSF1A-mediated inhibition of cytotoxicity in the L-929 mouse fibroblast cell line. The Neutralization titer (IC50) is typically 0.5-1. 5 microg/mL in the presence of 0.3 ug/ml Recombinant Human TNFR1/TNFRSF1A, 0.2 ng/mL Recombinant Human TNFa and 1 microg/mL actinomycin D. Please Note: Optimal concentrations/dilutions should be determined by the end user.. Block (0.5 µg/ml), ELISA (0.2 µg/ml), Neut (0.3 mg/ml) Block: In a functional ELISA which immobilized recombinant Human TNFR1 at 0.2 ug/ml (100 µL/well) in the plate, the Rabbit anti-Human Monoclonal Antibody can block the binding of 0.5 ug/ml of biotinylated Human TNFa to human TNFR1, the EC50 is 4. 66 ug/ml. Neutralization: The neutralization activity of TNFR1/TNFRSF1A Neutralizing Antibody is Measured by its ability to neutralize TNFR1/TNFRSF1A-mediated inhibition of cytotoxicity in the L-929 mouse fibroblast cell line. The Neutralization titer (IC50) is typically 0.5-1. 5 µg/mL in the presence of 0.3 ug/ml Recombinant Human TNFR1/TNFRSF1A, 0.2 ng/mL Recombinant Human TNFa and 1 µg/mL actinomycin D. Please Note: Optimal concentrations/dilutions should be determined by the end user.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

R111

Unconjugated

...

TNFRSF1A

TNF receptor superfamily member 1A

CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF-R1, TNF-RI, TNFR-I, tumor necrosis factor binding protein 1, tumor necrosis factor receptor type 1, tumor necrosis factor-alpha receptor

Rabbit

IgG

-20°C or -80°C,2°C to 8°C

12352203