Anti-BMPR1A Antibody

HUABIO

Anti-BMPR1A Antibody

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

BMPR1A

bone morphogenetic protein receptor type 1A

10q23del, ACVRLK3, ALK-3, ALK3, BMPR-1A, CD292, SKR5, bone morphogenetic protein receptor type-1A, BMP type-1A receptor, activin A receptor, type II-like kinase 3, activin receptor-like kinase 3, bone morphogenetic protein receptor, type IA, serine/threonine-protein kinase receptor R5

Rabbit

IgG

Bone morphogenetic protein receptor type-1A

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161