Immunohistochemistry of paraffin-embedded Human skin tissue using CASP3 Monoclonal Antibody at dilution of 1:200.
CASP3 Monoclonal Antibody
E-AB-22213
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCASP3 Monoclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- UNSPSC12352203