![WB analysis of HeLa cells treated with camptothecin (2microM) lysate using GTX59551 Caspase 3 antibody [C33]. WB analysis of HeLa cells treated with camptothecin (2microM) lysate using GTX59551 Caspase 3 antibody [C33].](https://www.genetex.com/upload/website/prouct_img/normal/GTX59551/Caspase-3-antibody-C33-GTX59551-WB-1_18121409_343_w_23061123_868.webp)
WB analysis of HeLa cells treated with camptothecin (2microM) lysate using GTX59551 Caspase 3 antibody [C33].
Caspase 3 antibody [C33]
GTX59551
ApplicationsWestern Blot
Product group Antibodies
TargetCASP3
Overview
- SupplierGeneTex
- Product NameCaspase 3 antibody [C33]
- Delivery Days Customer9
- Application Supplier NoteWB: 0.5-4 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC33
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID836
- Target nameCASP3
- Target descriptioncaspase 3
- Target synonymsCPP32, CPP32B, SCA-1, caspase-3, CASP-3, CPP-32, PARP cleavage protease, SREBP cleavage activity 1, apopain, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, cysteine protease CPP32, procaspase3, protein Yama
- HostMouse
- IsotypeIgG1
- Protein IDP42574
- Protein NameCaspase-3
- Scientific DescriptionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimers disease. [provided by RefSeq, Aug 2017]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Increasing intratumor C/EBP-beta LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer. Salaroglio IC et al., 2018 Nov 27, J Exp Clin Cancer ResRead more
- Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma. Salaroglio IC et al., 2018 Dec, Mol Cancer TherRead more
- The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. Pinzon-Daza ML et al., 2014 Aug, J Cereb Blood Flow MetabRead more



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