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ProductsBack/Caspase 3 antibody - Orthogonal Validated
ICC/IF analysis of NT2 neurons using GTX00752 Caspase 3 antibody. Triply stained for the N-terminus of APP (with P2-1) or beta-gal (with anti- beta gal antibody), chromosomal DNA (Hoechst), and activated caspase 3 subunits (with GTX00752). Some neurons accumulating APP are strongly immunostained with GTX00752 (arrows), whereas neurons accumulating beta-gal are hardly labeled (arrowheads). Fixation : 4% PFA
ICC/IF analysis of NT2 neurons using GTX00752 Caspase 3 antibody. Triply stained for the N-terminus of APP (with P2-1) or beta-gal (with anti- beta gal antibody), chromosomal DNA (Hoechst), and activated caspase 3 subunits (with GTX00752). Some neurons accumulating APP are strongly immunostained with GTX00752 (arrows), whereas neurons accumulating beta-gal are hardly labeled (arrowheads). Fixation : 4% PFA
ICC/IF analysis of NT2 neurons using GTX00752 Caspase 3 antibody. Triply stained for the N-terminus of APP (with P2-1) or beta-gal (with anti- beta gal antibody), chromosomal DNA (Hoechst), and activated caspase 3 subunits (with GTX00752). Some neurons accumulating APP are strongly immunostained with GTX00752 (arrows), whereas neurons accumulating beta-gal are hardly labeled (arrowheads). Fixation : 4% PFA

Caspase 3 antibody - Orthogonal Validated

Research Use Only
GTX00752
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCASP3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Caspase 3 antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes the active form of human caspase 3, p20/p17 subunit but does not recognize the proenzyme p32.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID836
  • Target name
    CASP3
  • Target description
    caspase 3
  • Target synonyms
    apopain; CASP-3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; CPP32; CPP-32; CPP32B; cysteine protease CPP32; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimers disease. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203