Bio-Connect

COX4 antibody [GT6310]

GTX628886
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetCOX4I1
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Overview

  • Supplier
    GeneTex
  • Product Name
    COX4 antibody [GT6310]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT6310
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1327
  • Target name
    COX4I1
  • Target description
    cytochrome c oxidase subunit 4I1
  • Target synonyms
    COX IV-1, COX4, COX4-1, COXIV, COXIV-1, MC4DN16, cytochrome c oxidase subunit 4 isoform 1, mitochondrial, cytochrome c oxidase polypeptide IV, cytochrome c oxidase subunit IV
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP13073
  • Protein Name
    Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
  • Scientific Description
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Naeem S, Qi Y, Tian Y, et al. NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation. Toxicol Lett. 2020,326:1-10. doi: 10.1016/j.toxlet.2020.03.001
    Read this paper
  • Choi BW, Jeong YJ, Park SH, et al. Reverse Warburg Effect-Related Mitochondrial Activity and (18)F-FDG Uptake in Invasive Ductal Carcinoma. Nucl Med Mol Imaging. 2019,53(6):396-405. doi: 10.1007/s13139-019-00613-x
    Read this paper
  • Gu X, Qi Y, Feng Z, et al. Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Toxicol Lett. 2018,291:92-100. doi: 10.1016/j.toxlet.2018.04.012
    Read this paper
  • Jeong SA, Kim IY, Lee AR, et al. Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells. Oncotarget. 2015,6(25):21173-92.
    Read this paper