Histone H2A.XS139ph (phospho Ser139) antibody [GT1021]
GTX628996
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetH2AX
Overview
- SupplierGeneTex
- Product NameHistone H2A.XS139ph (phospho Ser139) antibody [GT1021]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1021
- Concentration1.05 mg/ml
- ConjugateUnconjugated
- Gene ID3014
- Target nameH2AX
- Target descriptionH2A.X variant histone
- Target synonymsH2A histone family member X; H2A.X; H2A/X; H2AFX; H2AX histone; histone H2A.x; histone H2AX
- HostMouse
- IsotypeIgG2a
- Modification TypePhosphorylated
- Scientific DescriptionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Lin CC et al., 2020 Jul, Cell Death DifferRead more
- Inhibition of B7-H3 reverses oxaliplatin resistance in human colorectal cancer cells. Zhang P et al., 2017 Aug 26, Biochem Biophys Res CommunRead more