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ProductsBack/Histone H2A.XS139ph (phospho Ser139) antibody

Histone H2A.XS139ph (phospho Ser139) antibody

Research Use Only
GTX127340
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetH2AX
Price on request
Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    Histone H2A.XS139ph (phospho Ser139) antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.16 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3014
  • Target name
    H2AX
  • Target description
    H2A.X variant histone
  • Target synonyms
    H2A histone family member X; H2A.X; H2A/X; H2AFX; H2AX histone; histone H2A.x; histone H2AX
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

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  • Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays. Huang S et al., 2019 Mar 15, RSC Adv
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  • Ouabain Induces DNA Damage in Human Osteosarcoma U-2 OS Cells and Alters the Expression of DNA Damage and DNA Repair-associated Proteins. Yang JL et al., 2021 Sep-Oct, In Vivo
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  • The killifish visual system as an in vivo model to study brain aging and rejuvenation. Vanhunsel S et al., 2021 Aug 17, NPJ Aging Mech Dis
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  • Pre-Treatment of Pterostilbene Enhances H2O2-induced Cell Apoptosis Through Caspase-dependent Pathway in Human Keratinocyte Cells. Cheng YC et al., 2021 Mar-Apr, In Vivo
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  • Loss-of-function of p53 isoform delta113p53 accelerates brain aging in zebrafish. Zhao T et al., 2021 Feb 4, Cell Death Dis
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  • Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability. Chao T et al., 2021 Nov, Autophagy
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  • Maslinic Acid Induces DNA Damage and Impairs DNA Repair in Human Cervical Cancer HeLa Cells. Lu KW et al., 2020 Dec, Anticancer Res
    Read more
  • p53 isoform delta113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis. Ye S et al., 2020 Jul 23, Cell Death Dis
    Read more
  • Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo. Wang YY et al., 2020 Mar 31, ACS Omega
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