Iba1 antibody [HL22]
GTX635363
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetAIF1
Overview
- SupplierGeneTex
- Product NameIba1 antibody [HL22]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL22
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID199
- Target nameAIF1
- Target descriptionallograft inflammatory factor 1
- Target synonymsAIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, protein G1
- HostRabbit
- IsotypeIgG
- Protein IDP55008
- Protein NameAllograft inflammatory factor 1
- Scientific DescriptionThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
- ReactivityHuman, Mouse, Porcine, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Iacono D, Murphy EK, Stimpson CD, et al. Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation. Sci Rep. 2023,13(1):21142. doi: 10.1038/s41598-023-48146-wRead this paper
- Brown TC, Crouse EC, Attaway CA, et al. Microglia are dispensable for experience-dependent refinement of visual circuitry. bioRxiv. 2023,:pii: 2023.10.17.562708. doi: 10.1101/2023.10.17.562708.Read this paper
- Wang HK, Su YT, Ho YC, et al. HDAC1 is Involved in Neuroinflammation and Blood-Brain Barrier Damage in Stroke Pathogenesis. J Inflamm Res. 2023,16:4103-4116. doi: 10.2147/JIR.S416239Read this paper
- Wong CE, Hu CY, Lee PH, et al. Sciatic nerve stimulation alleviates acute neuropathic pain via modulation of neuroinflammation and descending pain inhibition in a rodent model. J Neuroinflammation. 2022,19(1):153. doi: 10.1186/s12974-022-02513-yRead this paper
- Fan Z, Zhang W, Cao Q, et al. JAK2/STAT3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. Ecotoxicol Environ Saf. 2022,234:113372. doi: 10.1016/j.ecoenv.2022.113372Read this paper
- Zhang Y, Hou B, Liang P, et al. TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia. Cell Death Dis. 2021,12(12):1159. doi: 10.1038/s41419-021-04450-9Read this paper
- Yan H, Zhao H, Kang Y, et al. Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition. Neuropharmacology. 2021,194:108627. doi: 10.1016/j.neuropharm.2021.108627Read this paper
- Xiong LL, Tan YX, Du RL, et al. Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action. Am J Chin Med. 2021,49(3):677-703. doi: 10.1142/S0192415X21500312Read this paper
- Teng SW, Sung HY, Wen YC, et al. Potential surrogate quantitative immunomodulatory potency assay for monitoring human umbilical cord-derived mesenchymal stem cells production. Cell Biol Int. 2021,45(5):1072-1081. doi: 10.1002/cbin.11553Read this paper
Datasheet
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