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Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 (GTX27900) 7.5% SDS PAGE GTX102227 diluted at 1:10000
Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 (GTX27900) 7.5% SDS PAGE GTX102227 diluted at 1:10000
Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 (GTX27900) 7.5% SDS PAGE GTX102227 diluted at 1:10000

KAP1 antibody [N1N2], N-term

GTX102227
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetTRIM28
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Overview

  • Supplier
    GeneTex
  • Product Name
    KAP1 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.31 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10155
  • Target name
    TRIM28
  • Target description
    tripartite motif containing 28
  • Target synonyms
    KAP1, PPP1R157, RNF96, TF1B, TIF1B, TIF1beta, WT7, transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, KAP-1, KRAB [Kruppel-associated box domain]-associated protein 1, KRAB-interacting protein 1, KRIP-1, RING finger protein 96, RING-type E3 ubiquitin transferase TIF1-beta, TIF1-beta, nuclear corepressor KAP-1, protein phosphatase 1, regulatory subunit 157, transcriptional intermediary factor 1-beta
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13263
  • Protein Name
    Transcription intermediary factor 1-beta
  • Scientific Description
    The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Stolarova L, Kleiblova P, Zemankova P, et al. ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk. Clin Cancer Res. 2023,29(16):3037-3050. doi: 10.1158/1078-0432.CCR-23-0212
    Read this paper
  • Martinikova AS, Burocziova M, Stoyanov M, et al. Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma. Cells. 2020,9(9). doi: 10.3390/cells9092068
    Read this paper
  • Ochiai H, Hayashi T, Umeda M, et al. Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Sci Adv. 2020,6(25):eaaz6699. doi: 10.1126/sciadv.aaz6699
    Read this paper