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ProductsBack/MLKL antibody [HL1849]
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with MLKL antibody [HL1849] (GTX637574) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with MLKL antibody [HL1849] (GTX637574) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with MLKL antibody [HL1849] (GTX637574) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

MLKL antibody [HL1849]

GTX637574
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetMLKL
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Overview

  • Supplier
    GeneTex
  • Product Name
    MLKL antibody [HL1849]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL1849
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID197259
  • Target name
    MLKL
  • Target description
    mixed lineage kinase domain like pseudokinase
  • Target synonyms
    hMLKL, mixed lineage kinase domain-like protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NB16
  • Protein Name
    Mixed lineage kinase domain-like protein
  • Scientific Description
    This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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