Amorfrutin B [1174387-94-0]

AdipoGen Life Sciences

Amorfrutin B

10

1174387-94-0

Research Use Only

>97%

C26H32O4

408.5

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. The binding affinity constant to PPARgamma is 12 times lower than Amorfrutin A (Prod. No. AG-CN2-0462). Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Antimicrobial agent. - Chemical. CAS: 78916-42-4 and 1174387-94-0. Formula: C26H32O4. MW: 408.5. Isolated from Amorpha fruticosa. Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. The binding affinity constant to PPARgamma is 12 times lower than Amorfrutin A (Prod. No. AG-CN2-0462). Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Antimicrobial agent.

COC1=C(C\C=C(/C)CCC=C(C)C)C(O)=C(C(O)=O)C(CCC2=CC=CC=C2)=C1

-20°C,2°C to 8°C

12352200