Nordihydroguaiaretic acid [500-38-9] [500-38-9]

Chemodex

Nordihydroguaiaretic acid [500-38-9] [500-38-9]

10

500-38-9

Research Use Only

>97%

Warning

C18H22O4

302.37

Chemical. CAS: 500-38-9. Formula: C18H22O4. MW: 302.37. Nordihydroguaiaretic acid (NDGA) is a potent free radical scavenger, protecting cells and tissues from oxidative stress. It is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis. It is an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases. NDGA inhibits p300 and activates autophagy. This compound shows antioxidant, antimutagenic, anticancer, antiviral and anti-inflammatory characteristics mediated through multiple signaling pathways. - Nordihydroguaiaretic acid (NDGA) is a potent free radical scavenger, protecting cells and tissues from oxidative stress. It is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis. It is an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases. NDGA inhibits p300 and activates autophagy. This compound shows antioxidant, antimutagenic, anticancer, antiviral and anti-inflammatory characteristics mediated through multiple signaling pathways.

C(C(C(CC1=CC(O)=C(O)C=C1)C)C)C2=CC(O)=C(O)C=C2

2°C to 8°C,RT

12352200