More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/ITGAV Recombinant Monoclonal Antibody
IHC image of CSB-RA548303A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
IHC image of CSB-RA548303A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
IHC image of CSB-RA548303A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

ITGAV Recombinant Monoclonal Antibody

CSB-RA548303A0HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetITGAV
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Cusabio
  • Product Name
    ITGAV Recombinant Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4G7
  • Conjugate
    Unconjugated
  • Gene ID3685
  • Target name
    ITGAV
  • Target description
    integrin subunit alpha V
  • Target synonyms
    antigen identified by monoclonal antibody L230; CD51; integrin alpha-V; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; vitronectin receptor subunit alpha; VNRA; VTNR
  • Isotype
    IgG
  • Protein IDP06756
  • Protein Name
    Integrin alpha-V
  • Scientific Description
    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:19578119). ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

Related products

Product group Antibodies
RayBiotech
Anti-ITGAV Antibody144-02091
ApplicationsWestern Blot, ImmunoHistoChemistry
TargetITGAV
  • SizePrice
Product group Antibodies
Biomatik
Itgav Polyclonal AntibodyCAC11195
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
TargetITGAV
  • SizePrice
Product group Antibodies
Assay Genie
Integrin alpha V (ITGAV/CD51) Monoclonal AntibodyCAB19071
TargetITGAV
  • SizePrice
Western Blot analysis of HeLa cells using Integrin alphaV Polyclonal Antibody
Product group Antibodies
Cusabio
ITGAV AntibodyCSB-PA003047
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman, Mouse
TargetITGAV
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
ITGAV/Integrin Alpha V/CD51 Antibody (HRP)LS-C671371
TargetITGAV
  • SizePrice
Product group Antibodies
Absolute Antibody
Anti-alpha-V integrin [EM01309]Ab00887-1.1
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
TargetITGAV
  • SizePrice
Product group Antibodies
Nordic-MUbio
Mouse anti Human vitronectin receptor CD51MUB2011P
ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
TargetITGAV
  • SizePrice
Figure 1. Western blot analysis of Integrin alpha V/ITGAV using anti-Integrin alpha V/ITGAV antibody (A01561-2). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human A549 whole cell lysates, Lane 2: human A431 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Integrin alpha V/ITGAV antigen affinity purified polyclonal antibody (Catalog # A01561-2) at 0.25 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Integrin alpha V/ITGAV at approximately 130-140KD. The expected band size for Integrin alpha V/ITGAV is at 130KD.
Product group Antibodies
Boster Bio
Anti-Integrin alpha V/ITGAV Antibody Picoband(r)A01561-2-CARRIER-FREE
ApplicationsFlow Cytometry, Western Blot, ELISA
TargetITGAV
  • SizePrice
Product group Antibodies
References
GeneTex
Integrin alpha V antibody [C2C3], C-termGTX100789
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetITGAV
  • SizePrice
Anti-ITGAV Antibody
Product group Antibodies
Antibodies.com
Anti-ITGAV AntibodyA37579
ApplicationsWestern Blot, ImmunoHistoChemistry
  • SizePrice